REBYOTA has confirmed 97% coverage for commercially and government-insured patients.* LEARN MORE

*REBYOTA Connect Benefits Verifications for commercially AND government-insured patients through June 15, 2023.

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The ordering process for REBYOTA
is streamlined to integrate efficiently into your operational workflow.

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There are multiple ways to obtain REBYOTA for your patients. REBYOTA is available for order through a network of specialty distributors (SDs). Administration is also available via REBYOTA @ Home or dispensed via a specialty pharmacy (SP). There may be payer-dependent requirements—running a benefits verification is the best way to confirm.

What you need to know to set up your account and order REBYOTA


This step is only needed if you don’t have an in-network Specialty Distributor account currently set up:

Prior to ordering REBYOTA for your patients, you will need to ensure you have an SD account within our network. We have provided a couple steps to get you started.

Identify which Specialty Distributor you would like to use within the network

The SD network account set up information chart below contains the specific contact information you will need to begin the process with your preferred SD.

  • Each SD has its own application process, turnaround time, and list of documentation that is needed to submit an order
  • Address verification may be required



Tel: 1-800-543-2111
Online portal:

Cardinal Health™
Metro Medical™

Tel: 1-800-768-2002
Online ordering portal:

  • Visit On the first screen, click on “Request information
    or set up an account” in the red box
  • Fill out the form and someone will contact you
  • If you have any questions during account registration, customers can call
    customer service at: 800-768-2002

Cardinal Specialty

Tel: 1-866-677-4844
Online Portal*:
*Online portal is for hospitals and pharmacies only; physician offices must call to initiate an account.


Tel: 1-877-599-7748

McKesson Specialty

McKesson Plasma and Biologics

McKesson Specialty Health

Optum Frontier

Tel: 1-833-754-6457

May take a minimum 72 hours for an account set up.


Once you have set up your account with your preferred SD, you can order REBYOTA.

When ordering REBYOTA from a Specialty Distributor, please keep in mind:

  • Orders placed on Monday–Thursday before 3:00 PM ET will arrive by 10:30 AM local time the following day
  • Orders placed Friday by 3:00 PM ET will arrive Tuesday by 10:30 AM in the local time zone
  • Orders outside of this standard window are available upon request, including Saturday or Monday delivery
  • Ferring has worked with SDs on extended payment terms. Inquire with your SD



Tel: 1-800-543-2111
Hours: Monday–Thursday, 8:00 AM–7:00 PM ET and Friday, 8:00 AM–5:00 PM ET

Cardinal Health™
Metro Medical™

Tel: 1-800-768-2002
Online Ordering Portal:

Cardinal Specialty

Tel: 1-855-855-0708
Hours: Monday–Friday, 8:00 AM–7:00 PM ET


Tel: 1-877-599-7748
Fax: 1-888-227-8158
Hours: Monday–Friday, 8:30 AM–5:30 PM ET

McKesson Specialty

McKesson Plasma and Biologics
Tel: 1-877-625-2566
Fax: 888-752-7626
Online Ordering Portal:
Hours: 9:00 AM–7:30 PM ET

McKesson Specialty Health
Tel: 1-855-477-9800
Fax: 800-800-5673
Online Ordering Portal:
Hours: 8:00 AM–8:00 PM ET

Optum Frontier

Tel: 1-833-754-6457

REBYOTA contains live microorganisms; it is important to follow proper storage requirements:

  • REBYOTA can stay in the unopened orange shipper box up to 5 days from date on box
  • Follow unpacking instructions printed on the orange shipper box for storage and thawing requirements
  • AEROSAFE will facilitate box returns with a phone call 1-2 days after receipt

– Tel: 1-585-328-2140

Shipping box filled with REBYOTA

REBYOTA @ Home Powered by Ferring

Patients may now receive treatment through our new REBYOTA @ Home program. If you are unable to administer in your office, your patients can still benefit from treatment via home health.

Follow these steps to begin enrollment:

  • Complete an enrollment form at
  • Check the @ Home box on the form
  • Please call 1-877-REBYOTA (1-877-732-9682) for any questions

REBYOTA may be dispensed via specialty pharmacies

Please work with your SP on logistics, handling, and their specific returns and replacement policies.


  • Optum Frontier Therapies: Tel: 1-855-768-9727. Hours: 24/7
  • Accredo: Prescription Tel: 1-866-759-1557. Customer Service Tel: 1-877-626-1511. Hours: 9:00 AM-11:00 PM ET
REBYOTA support and reimbursement icon

For any product questions or to inquire about a direct purchase option via credit card, please call 1-877-REBYOTA (1-877-732-9682)

For any product questions or to inquire about a direct purchase option,

REBYOTA support and reimbursement icon

please call 1-877-REBYOTA (1-877-732-9682)




How supplied

REBYOTA and the administration set are shipped together in a box. Each box may contain up to 6 cartons of REBYOTA and up to 6 administration sets. Each carton of REBYOTA (NDC 55566-9800-2) contains a single dose.

Storage and

REBYOTA contains live microorganisms. It is important to follow the storage requirements.
Upon Receipt: Store the REBYOTA carton in an ultracold freezer (-60°C to -90°C, -76°F to -130°F). Alternatively, store in a refrigerator (2°C to 8°C, 36°F to 46°F) for up to 5 days (including thaw time). Do not refreeze REBYOTA after thawing. Store the administration set at 10°C to 34°C (50°F to 93°F). DO NOT store the administration set in the freezer.
Before Using: Prior to use, thaw REBYOTA completely by placing carton in a refrigerator (2°C to 8°C, 36°F to 46°F) for approximately 24 hours. Do not refreeze REBYOTA after thawing. Dispose of all components in medical waste.

Carton size

Product box: 9 7/16” x 5 6/16” x 1”

Tube kit box: 9 7/16” x 5 6/16” x 1”

Combined: 18 14/16” x 5 12/16” x 2”

Carton weight

Product: 0.264 kg each
Admin Set: 0.09 kg each

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REBYOTA Support and Reimbursement

Support for providers as well as patients.

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Why Rebyota

Answers to REBYOTA questions including administration, safety, patient expectations, and more.

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REBYOTA (fecal microbiota, live – jslm) is indicated for the prevention of recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older, following antibiotic treatment for recurrent CDI.
Limitation of Use
REBYOTA is not indicated for treatment of CDI.


Do not administer REBYOTA to individuals with a history of a severe allergic reaction (eg, anaphylaxis) to any of the known product components.
Warnings and Precautions
Transmissible infectious agents

Because REBYOTA is manufactured from human fecal matter, it may carry a risk of transmitting infectious agents. Any infection suspected by a physician possibly to have been transmitted by this product should be reported by the physician or other healthcare provider to Ferring Pharmaceuticals Inc.
Management of acute allergic reactions
Appropriate medical treatment must be immediately available in the event an acute anaphylactic reaction occurs following administration of REBYOTA.
Potential presence of food allergens
REBYOTA is manufactured from human fecal material and may contain food allergens. The potential for REBYOTA to cause adverse reactions due to food allergens is unknown.
Adverse Reactions
The most commonly reported (≥3%) adverse reactions occurring in adults following a single dose of REBYOTA were abdominal pain (8.9%), diarrhea (7.2%), abdominal distention (3.9%), flatulence (3.3%), and nausea (3.3%).
Use in Specific Populations
Pediatric Use
Safety and efficacy of REBYOTA in patients below 18 years of age have not been established.
Geriatric Use
Of the 978 adults who received REBYOTA, 48.8% were 65 years of age and over (n=477), and 25.7% were 75 years of age and over (n=251). Data from clinical studies of REBYOTA are not sufficient to determine if adults 65 years of age and older respond differently than younger adults.

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Please click here for full Prescribing Information.

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